中德临床肿瘤学杂志（英文版）2006，Vol.5Issue(4)：257-260,4.
Correlation of the Appearances of DSA with VEGF Expression and Its Clinical Significance in Patients with Primary Hepatocellular Carcinoma
Correlation of the Appearances of DSA with VEGF Expression and Its Clinical Significance in Patients with Primary Hepatocellular Carcinoma
CHEN Fangman 1JIAO Xudong 1DU Fang1
作者信息
- 1. Department of Radiology, Yijishan Hospital of Wannan Medical College, Wuhu 241001, China
- 折叠
摘要
Abstract
Objective: To investigate the relationship between the appearances of digital subtraction angiography (DSA) and the serum level of vascular endothelial growth factor (VEGF) in patients with primary hepatocellular carcinoma (HCC). Methods: 24 HCC patients, 30 times DSA were examined, serum VEGF level was measured with the quantitative enzyme linked immunosorbent assay (ELISA) in patients and healthy control subjects in this study. Results: Among DSA for 24 patients with HCC, 18 of 24 cases showed hepatic artery blood supply of tumor. Four of 24 cases showed portal vein blood supply of tumor,1 of 24 cases showed superior mesenteric artery blood supply of tumor and artery-venous shunt formation, and there was no blood supply to tumor in one case. Serum VEGF level in HCC[(χ+s)194.5±14.2] ng/L was significant elevated to those in patients comparing with those of the normal controls (132.4±47.9)ng/L and marked differences (P＜0.01). Conclusion: During the cases for plenty blood supply or arteryvenous shunt formation in patients with HCC, serum VEGF level markedly elevated in the patients of HCC. VEGF expression was significantly related to intrahepatic dissemination, recurrence and metastasis in patients with HCC.关键词
hepatocellular carcinoma (HCC)/digital subtraction angiography (DSA)/Vascular Endothelial Growth Factor (VEGF)Key words
hepatocellular carcinoma (HCC)/digital subtraction angiography (DSA)/Vascular Endothelial Growth Factor (VEGF)分类
医药卫生引用本文复制引用
CHEN Fangman,JIAO Xudong,DU Fang..Correlation of the Appearances of DSA with VEGF Expression and Its Clinical Significance in Patients with Primary Hepatocellular Carcinoma[J].中德临床肿瘤学杂志（英文版）,2006,5(4):257-260,4.
