中德临床肿瘤学杂志（英文版）2006，Vol.5Issue(4)：261-267,7.
Influence of Perioperative Blood Transfusion on Prognosis in Patients with Colon Cancer
Influence of Perioperative Blood Transfusion on Prognosis in Patients with Colon Cancer
LIANG Han 1WANG Xiaona 1WANG Baogui 1PAN Yuan 1LIU Ning 1WANG Dianchang 1HAO Xishan1
作者信息
- 1. Department of Gastrointestinal Oncological Surgery, Tianjin Cancer Hospital, Tianjin Medical University, Tianjin 300060, China
- 折叠
摘要
Abstract
Objective: To explore the influence of perioperative blood transfusion on the postoperative survival of patients with colon cancer. Methods: Univariate and multivariate retrospective analyses were performed on the survival in a total of 723 colon cancer patients which were treated surgically during a period of 10 years. Results: Kaplan-Meicr estimates showed that more than 800 mL perioperative blood transfusion was the survival predictor. Blood transfusion influenced significantly the prognosis of patients 40 years old and younger, those undergoing helicoloectomy left side, those with papillary adenocarcinoma,those with big tumors (diameter ≥8 em), those with stage I tumors, those with lymphatic node metastases and those without liver metastases. In multivariate analysis only the tumor location, radicality of operation, lymphatic invasion, liver metastasis, depth of tumor invasion and TNM stage retained their significance. Conclusion: Perioperative blood transfusion is the prognostic factor for patients with colon cancer to some extent. The indication of blood transfusion must be restricted strictly, specially in patients younger than 40 years old, with right side lesion, papillary adenocarcinoma, big tumors (diameter ≥8 em), stage I tumors and lymphatic node metastases or without liver metastases. But perioperative blood transfusion may not be deleterious for patients with staging Ⅳ disease and with distant metastases.关键词
cancer/colon/surgery/blood transfusion/prognosisKey words
cancer/colon/surgery/blood transfusion/prognosis分类
医药卫生引用本文复制引用
LIANG Han,WANG Xiaona,WANG Baogui,PAN Yuan,LIU Ning,WANG Dianchang,HAO Xishan..Influence of Perioperative Blood Transfusion on Prognosis in Patients with Colon Cancer[J].中德临床肿瘤学杂志（英文版）,2006,5(4):261-267,7.
