南京医科大学学报（英文版）2004，Vol.18Issue(5)：262-266,5.
磁共振弥散成像评价星形细胞瘤细胞密度的价值
Value of Magnetic Resonance Diffusion Weighted Imaging in Evaluating Cellular Density of Astrocytomas
陈军 1夏军 2周义成3
作者信息
- 1. 武汉大学人民医院放射科,武汉,430060,中国
- 2. 深圳市第二人民医院放射科,深圳,518035,中国
- 3. 华中科技大学同济医学院附属同济医院放射科,武汉,430030,中国
- 折叠
摘要
Abstract
Objective: To evaluate the value of apparent diffusion coefficients(ADC) in Magnetic Resonance diffusion weighted imaging (MR DWI) with echo-planar technique in depicting the tumor cellularity and grading of astrocytomas. Methods: Thirty-four patients with astrocytomas( 18 male, 16 female, ages from 10-73 with average of 38.41 ) were examined by MRI and proved by surgery and pathology, and the number of grade Ⅰ - Ⅱ (low-grade) and grade Ⅲ-Ⅳ (high-grade) is 26 and 8 respectively. ADC values of astrocytomas were determined on MR DWI. Cellularity of astrocytomas was analyzed with Adobe Photoshop 7. 0 software. Results: Mean ADC values of high-grade astrocytomas( 7. 34 ± 2. 95) × 10-4mm2/s were significantly different from that of lowgrade astrocytomas(13. 76 ± 3. 31 ) × 10-4 mm2/s ( t = 4. 913, P ＜ 0. 001 ). Cellularity of high-grade astrocytomas (19. 81 ±9. 73 ) % were significantly higher than that of low-grade astrocytomas (4. 74 ± 2.96 ) % ( t = 4. 32,P =0. 003 ). ADC values of astrocytomas significantly negatively correlated with their cellularities ( r = - 0. 535, P =0. 001 ). Conclusion: The cellularities of astrocytomas contribute very much to ADC values in MR DWI. MR DWI is very valuable in predicting and evaluating the cellularity of astrocytomas. MR DWI might have a potential in predicting the degree of astrocytomas.关键词
胶质瘤/星形细胞瘤/磁共振成像/磁共振弥散加权成像/回波平面技术/细胞密度Key words
glioma/astrocytoma/MRI/magnetic resonance diffusion weighted imaging/echo-planar technique/cellularity分类
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陈军,夏军,周义成..磁共振弥散成像评价星形细胞瘤细胞密度的价值[J].南京医科大学学报（英文版）,2004,18(5):262-266,5.
