中国现代医学杂志2003，Vol.13Issue(23)：26-28,32,4.
MCP-1在大鼠视网膜缺血再灌注损伤中的表达及意义研究
Research of MCP-1 expression in rat's retina injured by ischemia-reperfusion
游志鹏 1姜德咏 1李国栋 1赵宏伟1
作者信息
- 1. 中南大学湘雅二医院眼科,长沙,410011
- 折叠
摘要
Abstract
Objective:The retina ischemia- reperfusion injury is caused by many factors. A lot of cell factors take part in it. Many researches suggest MCP - 1 has special effect on leukocyte and lymphocyte. The research try to study the effect of MCP - 1 in rat's retina ischemia- reperfusion injury. Methods: To employ the rat's retina ischemia- reperfusion model and use SABC method to test the expression of MCP- 1 on retina. Results: There was no MCP - 1 expressed in retina after ischemia- reperfusion injury for one hour. MCP- 1 began to express in retina after ischemia- reperfusion injury for six hours, and expressed at most after ischemia- reperfusion injury for 24 hours. Then it began to decrease in 48 hours after ischemia - repeffusion injury, but it still expressed in retina in seventy- two hours after ischemia- reperfusion injury. Conclusions: MCP- 1 plays an important role in rat's retina ischemia- reperfusion injury.关键词
MCP-1/视网膜/缺血再灌注损伤Key words
MCP- 1/ischhemia- reperfusion injury/retina分类
医药卫生引用本文复制引用
游志鹏,姜德咏,李国栋,赵宏伟..MCP-1在大鼠视网膜缺血再灌注损伤中的表达及意义研究[J].中国现代医学杂志,2003,13(23):26-28,32,4.
