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血清和脑脊液中脂肪阿拉伯酸甘露聚糖抗体检测对结核性脑膜炎诊断的价值

郑智远 陈琼 海镇环 贺铁生

中国现代医学杂志2001,Vol.11Issue(3):26-29,4.
中国现代医学杂志2001,Vol.11Issue(3):26-29,4.

血清和脑脊液中脂肪阿拉伯酸甘露聚糖抗体检测对结核性脑膜炎诊断的价值

VALUE OF DETECTING LIPOPARABINOMANNAN-IgG IN SERUM AND CEREBROSPINAL FLUID FOR DIAGNOSIS OF TUBERCULOUS

郑智远 1陈琼 1海镇环 1贺铁生1

作者信息

  • 1. 中南大学湘雅医院呼吸内科
  • 折叠

摘要

Abstract

Objective:To ascertain the value of lipoarabinomannan-IgG(LAM-IgG) determination in the diagnosis of tuberculous meningitis. Methods:LAM-IgG in serum and cerebrospinal fluid was detected with enzyme-linked immunosorbent assay. Results: In 77 patients with tuberculous meningitis,The positive rate of LAM-IgG in serum was 45.459% ,the positive rate in 30 control cases was 3.33% ,the specificity was 96.67% ;the positive rate of LAM-IgG in cerebrospinal fluid was 48.05% ,the specificitywas 100 %, their differences were not remarkable (χ2 = 0. 0714 , 0. 90 > P > 0.75). Detecting LAM-IgG in serum and cerebrospinalfluid at same time, the positive rate was 55. 84 %, the specificity was 96.67 %, comparing with the positive rate of LAM-IgG in cerebrospinal fluid,their difference was remarkable (χ2= 4.1667,P< 0.05). Conclusions: Detection of LAM-IgG in serum or cerbrospinal fluid have importance clinic value for diagnosing tuberculous meningitis,and detecting LAM-IgG in serum and cerebrospinalfluid at same time can increase diagnostic rate of tuberculous meningitis.

关键词

结核性脑膜炎/血清/脑脊液/脂肪阿拉伯酸甘露聚糖抗体

分类

医药卫生

引用本文复制引用

郑智远,陈琼,海镇环,贺铁生..血清和脑脊液中脂肪阿拉伯酸甘露聚糖抗体检测对结核性脑膜炎诊断的价值[J].中国现代医学杂志,2001,11(3):26-29,4.

中国现代医学杂志

1005-8982

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