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结肠癌肝转移动脉灌注化疗与静脉化疗疗效评价

蒋一鸣 朱士驹 蔡含 奉典旭 韩峰

同济大学学报(医学版)2001,Vol.22Issue(2):27-28,2.
同济大学学报(医学版)2001,Vol.22Issue(2):27-28,2.

结肠癌肝转移动脉灌注化疗与静脉化疗疗效评价

Evaluation of Therapeutic Effect of Hepatic Arterial Infusion or Venous Chemotherapy in Treatment of Liver Metastasis from Colon Cancer

蒋一鸣 1朱士驹 1蔡含 1奉典旭 1韩峰1

作者信息

  • 1. 上海市普陀区中心医院普外科,
  • 折叠

摘要

Abstract

Objective To evaluate the therapeutic effect of hepatic arterial infusion and venous chemotherapy in the treatment of patients with liver metastases from colon cancer.Methods Sixty-four patients with liver metastases from colon cancer were randomly divided into hepatic arterial infusion (HAI) group and venous chemotherapy (VC) group. FAM chemtherapy protocol was used in both two groups. CR, PR, RR and 1-, 2-, 3-year survival rates in two groups were analyzed.Results CR, PR, RR in HAI group was significantly higher than that in VC group (20% vs. 8.6%; 47.5% vs. 22.3%; 67.5% vs. 31.7%, P<0.05, respectively). 1-,2-, and 3-year survival rates in HAI group were also significantly higher than those in VC group (84.4% vs. 21.9%; 59.4% vs. 6.3%; 34.4% vs. 0%, P<0.05, respectively).Conclusion HAI was superior to VC group in the treatment of liver metastases from colon cancer.

关键词

结肠肿瘤/肝转移/肝动脉灌注/静脉化疗

分类

医药卫生

引用本文复制引用

蒋一鸣,朱士驹,蔡含,奉典旭,韩峰..结肠癌肝转移动脉灌注化疗与静脉化疗疗效评价[J].同济大学学报(医学版),2001,22(2):27-28,2.

同济大学学报(医学版)

1008-0392

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