中国肿瘤生物治疗杂志2000,Vol.7Issue(4):273-274,2.
人参皂甙与IL-2协同诱导PBMC对恶性脑胶质瘤细胞杀伤活性研究
Cytotoxicity of GS and IL-2 Activated PBMC to Malignant Glioma Cells
摘要
Abstract
Objective: To investigate a new method for improving the therapeutic effect on malignant glioma. Methods: A new type of killer cells, named GS-LAK, was induced by means of costimulating the peripheral ginsenoside(GS) and interleukin-2 (IL-2). Comparing with control group-LAK cells, cytotoxicity of GS-LAK cells against malignant glioma cells(BT325) was examined with MTI method. Results: It showed that GS-LAK cells exhibited some advantages over LAKcells in proliferation, cytotoxicity, as well as the utilizing of IL-2. Conclusion: The application of GS-LAK cells mightopen a new prospect to clinical therapeutic approach to malignant glioma.关键词
人参皂甙/IL-2/BT325/杀伤活性Key words
ginsenoside/IL-2/BT325/eytotoxicity分类
医药卫生引用本文复制引用
罗俊生,顾立学,席焕久,魏炳杰,刘兴波,邱建武,张鹏飞,单宏仁..人参皂甙与IL-2协同诱导PBMC对恶性脑胶质瘤细胞杀伤活性研究[J].中国肿瘤生物治疗杂志,2000,7(4):273-274,2.基金项目
本文为中国免疫学会推荐稿,受辽宁省教委科研基金(991721599)资助 (991721599)