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米糠多糖的提取纯化及其成分结构和活性分析

汪艳 吴曙光 周杰 徐伟 徐继红

生命科学研究2000,Vol.4Issue(3):273-277,5.
生命科学研究2000,Vol.4Issue(3):273-277,5.

米糠多糖的提取纯化及其成分结构和活性分析

Studies of Extraction and Purification Technique of RBS and Anti-tumor Effect Related to the Poly-saccharide

汪艳 1吴曙光 1周杰 1徐伟 1徐继红1

作者信息

  • 1. 第一军医大学药物研究所,中国广东广州 510515
  • 折叠

摘要

Abstract

Extraction methods and the physico-chemical properties and anti-tumor effect of RBS were studied. Polysaccharide RBS was prepared from rice bran with hot water extraction. Pure RBS was obtained as a fraction on Sepharose-Cl6B. Physico-chemical properties of RBS was studied by infrared spectral analysis,13C-NMR etc.RBS was given to Meth-A tumor-bearing Balb/c mice to test its anti-tumor activity. Physico-chemical properties of RBS were as follows: It was a kind of α-glucan having α-1,4 and α-1,6 gluco-sidic bond as a main frame. It was a white powder soluble in water. Inhibitive effect against Meth-A solid tumor was observed by oral administration of RBS.

关键词

米糠多糖/提取纯化/α-葡聚糖/抑瘤活性

Key words

rice bran polysaccharide(RBS)/extraction/purification/α-glucan/anti-tumor activity

分类

医药卫生

引用本文复制引用

汪艳,吴曙光,周杰,徐伟,徐继红..米糠多糖的提取纯化及其成分结构和活性分析[J].生命科学研究,2000,4(3):273-277,5.

基金项目

广东省自然科学基金资助项目(960366) (960366)

生命科学研究

OACSCDCSTPCD

1007-7847

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