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肝门区域低温冷冻的实验效应

刘建平 区庆嘉 陈双 罗葆明 蒋宁一

解放军医学杂志2001,Vol.26Issue(4):275-276,2.
解放军医学杂志2001,Vol.26Issue(4):275-276,2.

肝门区域低温冷冻的实验效应

THE EXPERIMENTAL EFFECTS OF FREEZING THE AREA OF FIRST PORTA HEPATIS IN PIGS

刘建平 1区庆嘉 1陈双 1罗葆明 1蒋宁一1

作者信息

  • 1. 中山医科大学孙逸仙纪念医院
  • 折叠

摘要

Abstract

To investigate the effects of freezing the area of first porta hepatis which involves Glisson duct system,16 pigs were randomly divided into 2 groups. Group A:structures of the first porta hepatis were frozen by a dish-like cryoprobe (D=3.0cm) with temporary blockage of hepatic portal blood during freezing,the temperature at the end of 1,2,3minutes of cryotherapy was -50℃,-110℃,-131℃.Group B:sham operation,only with hepatic portal blockage for 3 minutes. Liver function tests,99mTc-EHIDA scintiscanning,and pathological observation were used to evaluate the effects of the cryosurgery postoperatively.The results showed that the bile duct systems on first porta hepatis were severely destroyed by the cryosurgery,the cryoimpairment of common bile duct and/or common hepatic duct led to complications of progressive, irreversible, cryptic necrosis, fistula and pyogenic angiocholitis. The large freezing necrotic lesion in the porta hepatis might compress the portal vein. The perfect protection of biliary system should be accomplished in the cryosurgery of the first porta hepatis to avoid severe complications.

关键词

/冷冻外科手术/超声检查

分类

医药卫生

引用本文复制引用

刘建平,区庆嘉,陈双,罗葆明,蒋宁一..肝门区域低温冷冻的实验效应[J].解放军医学杂志,2001,26(4):275-276,2.

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