中国中西医结合杂志2001，Vol.21Issue(4)：277-279,3.
心康口服液对实验性小鼠柯萨奇B3
病毒性心肌炎的实验研究
Experimental Study on Effect of Xinkang Oral Liquid on Coxsackie B3 Viral Myocarditis in Mice
赵红 1万素君 2徐新林 1楮雁 3黄霞珍 2阮英茆3
作者信息
- 1. 中国医学科学院中国协和医科大学心血管病研究所阜外心血管病医院,
- 2. 中国中医研究院广安门医院
- 3. 中国医学科学院中国协和医科大学心血管病研究所阜外心血管病医院
- 折叠
摘要
Abstract
To study the therapeutic effect of Xinkang Oral Liquid (XKOL) in treating acute Coxsackie B3 viral myocarditis in mice. Methods: Viral myocarditis model was established by intraperitoneal inoculation with Coxsackie B3 virus. Mice were randomly divided into 4 groups randomly, the model group, the positive control group (treated with Ribavilin), the XKOL group and the normal control group. Body weight of mice was weighed at the 5th, 10th and 20th day. Weight, macro- and histopathologic changes of heart were observed by microscope and measured by morphometric quantification, and the data were treated statistically. Results: In the XKOL group, the body weight of mice increased, the degree of myocardial necrosis mild and small in size, which has been repaired more completely, the antiviral effect was found in XKOL group. Conclusion: XKOL has definite therapeutic effect on viral myocarditis, its effect is better than Ribavilin in protecting myocardium and anti-virus.关键词
病毒性心肌炎/心康口服液/组织形态学分类
医药卫生引用本文复制引用
赵红,万素君,徐新林,楮雁,黄霞珍,阮英茆..心康口服液对实验性小鼠柯萨奇B3
病毒性心肌炎的实验研究[J].中国中西医结合杂志,2001,21(4):277-279,3.
