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传统型和视神经脊髓型多发性硬化临床特征的比较

程晓娟 姜国鑫 许丽珍 赵合庆 赵忠 王薇 程琦

内科理论与实践2009,Vol.4Issue(4):278-281,4.
内科理论与实践2009,Vol.4Issue(4):278-281,4.

传统型和视神经脊髓型多发性硬化临床特征的比较

Comparison of clinical characteristics between patients with opticospinal and conventional multiple sclerosis

程晓娟 1姜国鑫 2许丽珍 3赵合庆 4赵忠 5王薇 6程琦7

作者信息

  • 1. 上海交通大学医学院附属瑞金医院神经内科,上海,200025
  • 2. 上海交通大学公共卫生学院流行病学教研室,上海,200025
  • 3. 瑞典卡罗林斯卡医学院公共卫生系,斯德哥尔摩,17177
  • 4. 苏州大学附属第一医院神经内科,江苏,苏州,215006
  • 5. 苏州大学附属第二医院神经内科,江苏,苏州,215004
  • 6. 苏州市立医院,东区神经内科,江苏,苏州,215001
  • 7. 苏州市立医院,本部神经内科,江苏,苏州,215002
  • 折叠

摘要

Abstract

Objective To compare the clinical characteristics between patients with opticospinal multiple sclerosis (OS-MS) and those with conventional multiple sclerosis (C-MS). Methods Clinical materials of 99 patients with MS diagnosed according to the McDonald criteria in Suzhou area were collected (C-MS: 73 cases; OS-MS: 26 cases) and analyzed in coordination with results of laboratory examinations. Results Compared to patients with C-MS, female was more preponderant and prognosis was poorer in patients with OS-MS, initial symptoms were more frequently with visual deterioration and motor weakness, and the prevalence of motor weakness, sensory symptoms and visual deterioration during the course of disease was higher. No significant difference was found in age at onset and course of disease between the two groups. Conclusions There are some differences of certain clinical characteristics between patients with C-MS and OS-MS.

关键词

多发性硬化/视神经脊髓型多发性硬化/传统型多发性硬化/临床特征

Key words

Multiple sclerosis/Opticospinal multiple sclerosis/Conventional multiple sclerosis/Clinical features

分类

医药卫生

引用本文复制引用

程晓娟,姜国鑫,许丽珍,赵合庆,赵忠,王薇,程琦..传统型和视神经脊髓型多发性硬化临床特征的比较[J].内科理论与实践,2009,4(4):278-281,4.

基金项目

国家自然科学基金(项目编号:30872179) (项目编号:30872179)

上海市科委国际合作项目(项目编号:08410702200、054107064):上海市重点学科建设项目(项目编号:08GWEX0201) (项目编号:08410702200、054107064)

内科理论与实践

OACSTPCD

1673-6087

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