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幽门螺杆菌对胎儿胃粘膜的粘附作用

代丽萍 王凯娟 段广才 张建中

河南医科大学学报2001,Vol.36Issue(3):279-281,3.
河南医科大学学报2001,Vol.36Issue(3):279-281,3.

幽门螺杆菌对胎儿胃粘膜的粘附作用

Study on adhesion of Helicobacter pylori to stomach mucosa tissue

代丽萍 1王凯娟 1段广才 1张建中2

作者信息

  • 1. 河南医科大学流行病学教研室
  • 2. 中国预防医学科学院流行病学与微生物学研究所
  • 折叠

摘要

Abstract

Aim:To investigate the adhering ability and characteristics of Helicobacter pylori (HP) to gastric mucosa and the role of adhesion process in pathogenicity of HP.Methods: Ten HP strains were tested by adhering to stomach mucosa of 4 fetuses ageing from 6 to 8 months.Results: The average numbers of different HP strains adhering to fetal mucosa were very different.The numbers of HP on every tissue piece varied form 51 to 3 700. There were also significant differences in adhering numbers of HP strain in the same site of different fetus' stomaches and in different sites of one stomach. No matter how many germs which adhered to stomach,the gastric mucosa's pathological change of all corresponding patients exceeded middle degree.Conclusion: It is indicated that the number of HP adhered to stomach mucosa is influenced not only by the kinds and quantity of adhesion but also by the kinds and quantites of their corresponding receptors distributing on different gastric mucosa. Although adhesion of HP is a crucial progress in pathogenicity, the adhering ability of HP to stomach mucosa is not the only key factor.

关键词

幽门螺杆菌/粘附/胎儿//致病性

分类

医药卫生

引用本文复制引用

代丽萍,王凯娟,段广才,张建中..幽门螺杆菌对胎儿胃粘膜的粘附作用[J].河南医科大学学报,2001,36(3):279-281,3.

基金项目

河南省自然科学基金资助项目 984024100 ()

河南医科大学学报

OA北大核心CSCD

1671-6825

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