中国病理生理杂志2001，Vol.17Issue(3)：281-284,4.
α-黑色素细胞刺激素的抗炎机制
The anti-inflammatory mechanisms of α-melanocyte-stimulating hormone
陈波 1胡巢凤 1王华东 1林晨 2李楚杰1
作者信息
- 1. 暨南大学医学院 病理生理学教研室
- 2. 微生物学与免疫学教研室,
- 折叠
摘要
Abstract
α-MSH is an endogenous neuropetide that is effective of all categories of expreimental inflammation. The mechanisms underlying the anti-inflammatory influence of α-MSH are reviewed in the article. α-MSH suppresses inflammation in the CNS and periphery by downregulating the activation of NF-κB, then inhibiting production of proinflammatory cytokines, nitric oxide, chemokines and adhension molecules, and increasing synthesis of anti-inflammatory cytokines. α-MSH is useful in the treatment of many pathological situations in humans.关键词
MSH/细胞活素类/NF-κB/炎症分类
医药卫生引用本文复制引用
陈波,胡巢凤,王华东,林晨,李楚杰..α-黑色素细胞刺激素的抗炎机制[J].中国病理生理杂志,2001,17(3):281-284,4.
