国际眼科杂志2006，Vol.6Issue(2)：282-290,9.
中国和印度原发性先天性青光眼患者临床特点的对比研究
A comparison study of the clinical features between Chinese and Indian primary congenital glaucoma patients
李茅 1陈晓明 1刘娅利 1盘如刚 1刘东敬 1李妮1
作者信息
- 1. 610041,中国四川省成都市,四川大学华西医院眼科
- 折叠
摘要
Abstract
· AIM: To summarize the clinical features of Chinese primary congenital glaucoma and to investigate the discrepancies of the clinical features between the Chinese and Indian patients.congenital glaucoma patients were reviewed. The clinical features were summarized as several quantifiable clinical parameters and the severity of the disease was evaluated. Both the quantified clinical features and severity were statistically compared with those of the Indian patients, which were cited from the previous published articles.included in the study. In Chinese patients, sex ratio (male to female )was about 2:1, family history was presented in 3 patients (7.5%) and consanguinity was found in one patient (2.5%). The main symptoms and signs observed in Chinese patients spanned a wide spectrum of manifestations. The most frequent signs noted on the initial examination were enlarged eyeball (42.5%) and decreased visual acuity (35.0%). Compared with Indian patients, Chinese patients had a later onset, a delayed diagnosis, more severe corneal changes and more severe optic nerve damages (P＜0.01). The combined tabeculectomy and trabeculotomy operation was preferred by both Chinese and Indian doctors whereas a higher proportion of Indian patients received the combined operation (P＜0.01). The proportions of the severity grade were different between Chinese and Indian patients. Most Chinese patients were in the severe grade while most Indian patients were in the very severe grade (P＜0.01).patients were sporadic and non-consanguineous.Compared with Indian patients, Chinese patients had a relative later onset, a delayed diagnosis and treatment.More attempts are needed in Chinese PCG prevention and treatment.关键词
原发性先天性青光眼/临床特点/中国人/印度人Key words
primary congenital glaucoma/clinical features/Chinese/Indian分类
医药卫生引用本文复制引用
李茅,陈晓明,刘娅利,盘如刚,刘东敬,李妮..中国和印度原发性先天性青光眼患者临床特点的对比研究[J].国际眼科杂志,2006,6(2):282-290,9.
