中国现代医学杂志2004，Vol.14Issue(2)：28-32,5.
sIL-2R和16在肝移植术后早期急性排斥和细菌感染中的诊断价值
Significance of sIL-2R and IL-6 in the diagnosis of acute rejection and bacterial infection during liver transplantation
王港 1张同琳1
作者信息
- 1. 北京大学第三医院,普外科,北京,100083
- 折叠
摘要
Abstract
Objective :To investigate the significance of soluble interleukin -2 receptor (sIL- 2R) and interleukin -6 (IL- 6) in plasma and bile in the diagnosis of acute rejection and bacterial infection in the early stage after liver transplantation. Methods: 20 patients undergoing orthotopic liver transplantation were included in our study.SIL- 2R and IL- 6 levels in plasma and bile were measured perioperatively by enzyme- linked immunoadsorbent assay. Results: Plasma sIL - 2R elevated prior to the pathological diagnosis of acute rejection and daily increase of IL6 in bile was more than 450 pg/ml ,which was seen in 3 of 4 patients prior to or at the onset of acute rejection. IL6 in plasma increased significantly when bacterial infection occurred, while slL- 2R in bile correlated with neither acute rejection nor bacterial infection. Conclusions: Measurements of sIL- 2R and IL- 6 may be useful in diagnosing acute rejection and bacterial injection during liver transplantation.关键词
肝移植/急性排斥/细菌感染/可溶性白细胞介素2受体/白细胞介素6Key words
Liver transplantation/Acute rejection/Bacterial infection/Soluble interleukin - 2 receptor/Interleukin - 6分类
医药卫生引用本文复制引用
王港,张同琳..sIL-2R和16在肝移植术后早期急性排斥和细菌感染中的诊断价值[J].中国现代医学杂志,2004,14(2):28-32,5.
