中德临床肿瘤学杂志(英文版)2008,Vol.7Issue(5):286-291,6.
MRI结合数字化钼靶诊断乳腺癌的临床研究
Clinical study of digital mammography,contrast-enhanced MRI as well as their combination in the diagnosis of breast cancer
Fang Ye 1Mengsu Zeng 1Fuhua Yan 1Wei Feng 1Meiling Zhou 1Renchen Li 1Wenfang Chen1
作者信息
- 1. Department of Radiology,Zhongshan Hospital,Fudan University,Shanghai 200032,China
- 折叠
摘要
Abstract
Objective:To compare the effectiveness of digital mammography and MRI in the detection and diagnosis of breast cancer and to assess the value of these modalities as well as the combination of the two.Methods:Sixty-seven patients with surgery and pathology proved breast lesion (malignant,n=32; benign,n=46) underwent digital mammography and MRI,the pulse sequences included T1WI,T2Wl,diffuse weighted imaging (DWI),and dynamic contrast-enhanced MRI before surgery.Of the results of these two modalities,all lesions were classified into 5 groups according to BI-RADS classification,and the imaging findings were correlated to histopathology.The sensitivity and specificity of each modality as well as the combination of the two were calculated.Results:Of these 78 breasts lesions,The sensitivity was 78.13%% (25/32) for digital mammography and 93.75% (30/32) for MRI (P>0.05).The specificity was 73.91%% (34/46) and 89.13% (41/46) accordingly (P<0.05),both of them showed statistical difference.The sensitivity and specificity was 98.63% and 97.16% respectively as these two modalities were used in combination.Conclusion:Digital mammography in combination with MRI is helpful in the diagnosis of breast cancer,the sensitivity and specificity was enhanced when compared to that of single modality.关键词
magnetic resonance imaging/ breast neoplasms/ mammographyKey words
magnetic resonance imaging/ breast neoplasms/ mammography分类
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Fang Ye,Mengsu Zeng,Fuhua Yan,Wei Feng,Meiling Zhou,Renchen Li,Wenfang Chen..MRI结合数字化钼靶诊断乳腺癌的临床研究[J].中德临床肿瘤学杂志(英文版),2008,7(5):286-291,6.