首页|期刊导航|中国海洋湖沼学报（英文版）|Chemical constituents of marine medicinal mangrove plant Sonneratia caseolaris
中国海洋湖沼学报（英文版）2009，Vol.27Issue(2)：288-296,9.DOI:10.1007/s00343-008-0138-9
Chemical constituents of marine medicinal mangrove plant Sonneratia caseolaris
Chemical constituents of marine medicinal mangrove plant Sonneratia caseolaris
摘要
Abstract
Twenty-four compounds including eight steroids (1-8), nine triterpenoids (9-16, 24), three flavonoids (20-22), and four benzenecarboxylic derivatives (17-19, 23) were isolated and identified from stems and twigs of medicinal mangrove plant Sonneratia caseolaris. The structures of the isolated compounds were determined by extensive analysis of their spectroscopic data. Among these metabolites, compounds 1, 4-20 and 22-24 were isolated and identified for the f'urst time from S. caseolaris. In the in vitro cytotoxic assay against SMMC-7721 human hepatoma cells, compound 21 (3',4',5,7-tetrahydroxyflavone)exhibited significant activity with IC50 2.8 μg/mL, while oleanolic acid (14), 3,3'-di-O-methyl ether ellagic acid (18), and 3,3',4-O-tri-O-methyl ether ellagic acid (19) showed weak activity. None of these compounds displayed significant antibacterial activites.关键词
mangrove/ Sonneratia caseolaris/ chemical constituents/ cytotoxic assayKey words
mangrove/ Sonneratia caseolaris/ chemical constituents/ cytotoxic assay分类
天文与地球科学引用本文复制引用
TIAN Minqing,DAI Haofu,LI Xiaoming,WANG Bingui..Chemical constituents of marine medicinal mangrove plant Sonneratia caseolaris[J].中国海洋湖沼学报（英文版）,2009,27(2):288-296,9.基金项目
Supported by the National Natural Science Foundation of China (No.30770234) （No.30770234）
Knowledge Innovation Program of Chinese Academy of Sciences (KZCX2-YW-211-04) （KZCX2-YW-211-04）
Department of Science and Technology of Shandong Province (No.2006GG2205023) （No.2006GG2205023）
