中国现代医学杂志2006，Vol.16Issue(19)：2884-2887,4.
不完全系统性红斑狼疮患者的随访研究及病情进展预测
Clinical outcome and predictors of disease evolution in patients with incomplete systemic lupus erythematosus
摘要
Abstract
[Objective] To describe the outcome and identify risk factors for evolution into complete systemic lupus erythematosus (SLE) within the population of incomplete lupus erythematosus (ILE). [Methord] Clinical and serologic manifestations of these patients were recorded in standardized formats and all patients were evaluated annually. [Results] Nineteen patients with ILE were included, during follow-up, eleven patients developed complete SLE. Hazard analyses showed that malar rash, photosensitivity and elevated anti-dsDNA were associated with SLE occurrence. [Conclusions] In this follow-up study of patients with ILE, 58% of ILE patients developed complete disease, but the SLEDAI score of all patients were very low, which suggested that ILE represents a mild spectrum of lupus. Malar rash, photosensitivity and elevated anti-dsDNA were predictors of complete SLE.关键词
系统性红斑狼疮/不完全系统性红斑狼疮/临床结果/危险因素Key words
systemic lupus erythematosus/incomplete systemic lupus erythematosus/clinical outcome/risk factors分类
医药卫生引用本文复制引用
李博,叶志中,庄俊汉,汪迅,张丽君,李剑松..不完全系统性红斑狼疮患者的随访研究及病情进展预测[J].中国现代医学杂志,2006,16(19):2884-2887,4.基金项目
Shenzhen key projects foundation assistance (No.2005C10) （No.2005C10）
