中国现代医学杂志2005,Vol.15Issue(19):2894-2896,2905,4.
1999~2003年洋葱伯克霍尔德菌分布及耐药性分析
Analysis of distribution and resistance of burkholderia cepacia to antibiotics from 1999~2003
李冬 1褚云卓 2陈佰义3
作者信息
- 1. 中国医科大学附属第一医院感染科,辽宁沈阳110001
- 2. 中国医科大学附属第一医院检验科,辽宁沈阳110001
- 折叠
摘要
Abstract
[Objective] To investigate the distribution and resistance of Burkholderia cepacia to antibiotics from 1999~2003, and give clinicians information on the effective therapy and prevention of Burkholderia cepacia infections. [Method] Strains of Burkholderia cepacia were isolated from specimens and identified by API system. KirbyBauer test was used for antibiotics susceptibility. [Results] Total 513 stains of Burkholderia cepacia were isolated.Burkholderia cepacia had been isolated in many departments and was especially common in the department of nephrology, department of urology and intensive care units (ICUs). The resistance to antibiotics is inclined to rise year by year in this study. The resistance to imipenem, ceftazidime, cefepime and amikacin rose from 5.0%, 8.4%,15.2% and 31.1% in 1999, to 44.9%, 34.6%, 40.3% and 66.3% in 2003 respectively. Burkholderia cepacia displayed the lowest resistance to cefoperazone/sulbactam and piperacillin/tozobatam. [ Conclusions] Burkholderia cepacia has become an important pathogen of nosocomial infection and is resistant to most antimicrobial agents. The continual resistance surveillance is very important for the effective therapy and prevention of Burkholderia cepacia infections.关键词
洋葱伯克霍尔德菌/耐药监测/院内感染Key words
burkholderia cepacia/resistance surveillance/nosocomial infection分类
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李冬,褚云卓,陈佰义..1999~2003年洋葱伯克霍尔德菌分布及耐药性分析[J].中国现代医学杂志,2005,15(19):2894-2896,2905,4.