生殖医学杂志2005，Vol.14Issue(z1)：29-32,4.
The outcomes of human blastocyst cryopreservation: vitrification using cryoloop versus slow-freezing method
The outcomes of human blastocyst cryopreservation: vitrification using cryoloop versus slow-freezing method
Sun Zheng-yi 1He Fang-fang 1Yu Qi 1Deng Cheng-yan 1Liu Mei-zhi1
作者信息
- 1. Department of Obstetrics & Gynecology, Peking Union Medical College Hospital,Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730,China
- 折叠
摘要
Abstract
Objective: To compare the outcomes of vitrification using cryoloop with slow-freezing method for human blastocyst cryopreservation.Methods: In IVF-ET cycles, supernumerary embryos were cultured to Day 5 or Day 6, blastocysts were cryopreserved by vitrification using cryoloops or slow-freezing method, then blastocyst survival rate and pregnant rate were compared.Results: 115 vitrified blastocysts from 39 cycles were warmed, 104(90.4%) blastocysts survived. After the transfer of 74 blastocysts in 38 cycles, 28(73.7%) women got clinically pregnant, 2(7.1%) of them suffered from miscarriage, 2 healthy babies were born in 2 deliveries, and the other 24 pregnancies are ongoing. As to slow-freezing method, 87 blastocysts from 21 cycles were thawed, 37(42.5%)of them survived, 28 blastocysts were transferred in 15 cycles, 6(40%) women got clinically pregnant, 1 of them miscarried, 3 healthy babies were born in 2 deliveries, and the other 3 pregnancies are ongoing.Conclusion: The survival rate and pregnant rate of vitrification using cryoloop are superior to traditional slow-freezing method, and the transfer cancel rate is lower than that of slow-freezing method. The miscarriage rate is similar in two methods.关键词
Blastocyst/Cryopreservation/VitrificationKey words
Blastocyst/Cryopreservation/Vitrification分类
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Sun Zheng-yi,He Fang-fang,Yu Qi,Deng Cheng-yan,Liu Mei-zhi..The outcomes of human blastocyst cryopreservation: vitrification using cryoloop versus slow-freezing method[J].生殖医学杂志,2005,14(z1):29-32,4.
