临床神经病学杂志2001，Vol.14Issue(1)：30-32,3.
戊四氮点燃大鼠模型海马结构内突触体素的变化
Change of synaptophysin in rat model hippocampal formation after pentylenetetrazol kindling
冯亚波 1姚红 1迟兆富2
作者信息
- 1. 山东省立医院神经内科
- 2. 山东医科大学附属医院神经内科
- 折叠
摘要
Abstract
Objective To study the plasticity of hippocampal formation in epilepsy.Methods The optical density (OD)of synaptophysin positive immunoreactive product was examined by image pattern analysis instrument in hippocampus of pentylenetetrazol induced kindling epileptic rats. The examined areas included CA1,CA3 and the dentate gyrus.Results The OD of synaptophysin positive immunoreactive product in hippocampal formation of kindling group was higher than the controls,especially in the mossy fiber layer of the area CA3 and the inner molecular layer in the dentate gyrus. Conclusion The change of synaptophysin resulted from kindling, it also could result in the molecular elements of kindling maintenance.关键词
点燃/海马结构/突触体素/癫痫/戊四氮分类
医药卫生引用本文复制引用
冯亚波,姚红,迟兆富..戊四氮点燃大鼠模型海马结构内突触体素的变化[J].临床神经病学杂志,2001,14(1):30-32,3.
