河南医科大学学报2001，Vol.36Issue(3)：305-308,4.
梗死前心绞痛对急性心肌梗死溶栓-再灌注的影响
Effect of pre-infarction angina on coronary thrombolysis-reperfusion in patients with acute myocardial infarction
张巧云 1李凌 2赵洛沙 2赵晓燕2
作者信息
- 1. 河南医科大学护理学院
- 2. 河南医科大学第一附属医院内科
- 折叠
摘要
Abstract
Aim：To explore the relationship between pre-infarction angina and coronary thrombolysis-reperfusion in patients with acute myocardial infarction（AMI）．Methods： By comparing the condition of 27 patients who had unstable angina during one week before AMI with that of 25 patients who had no pre-infarction angina，we found that the two groups did not differ significantly in terms of clinical base-line characteristics．The size of infarction was estimated based on the level of cardiacenzyme and ECC measurements （∑R，NQ）．The time of reopening was defined from the start of thrombolytic therapy to the time when ST-segment elevation abruptly decreased by 50％．Results：Reopening occurred within 30 min after the start of treatment in 33％ of the patients with pre-infarction angina，but in none of those without pre-infarction angina（P＜0．005）．Reopening rates at 60 min were 59％ and 36％ in the two groups，respectively（P＜0．005）．The duration of reperfusion were （49±16） min and （69±19） min respectively（P＜0．05）．The cardiac enzymatic indexes which reflected infarction size were all significantly lower in patients with pre-infarction angina than in those without （P＜0．05，respectively）．The ECG showed a higher R waves and a smaller numnber of Q waves in the group with pre-infarction angina the in the group without （P＜0．05，respectively）．Conclusion:The thrombolytic therapy is more effective and the size of infarction is smaller in patients with pre-infarction angina．The preinfarction angina could be regarded as a sensitive predictor for applying coronary thrombolysis promptly to patients with AMI．关键词
心肌梗死/梗死前心绞痛/溶栓疗法/再灌注分类
医药卫生引用本文复制引用
张巧云,李凌,赵洛沙,赵晓燕..梗死前心绞痛对急性心肌梗死溶栓-再灌注的影响[J].河南医科大学学报,2001,36(3):305-308,4.
