An animal model to create intervertebral disc degeneration characterized by radiography and molecular biologyOA
An animal model to create intervertebral disc degeneration characterized by radiography and molecular biology
Objectives: To develop a rabbit model of intervertebral disc degeneration that more exactly simulates the pathological changes of human intervertebral disc degeneration. Methods: Twelve New Zealand white rabbits were utilized…查看全部>>
Objectives: To develop a rabbit model of intervertebral disc degeneration that more exactly simulates the pathological changes of human intervertebral disc degeneration. Methods: Twelve New Zealand white rabbits were utilized to establish three different disc injury models according to the following protocol; group A: anulus punctures were done with a 18-gauge needle at L2-L3 and L5-L6; Group B: intradiscal injection of interleukin-l IL-lβ with a 23-gauge ne…查看全部>>
Zhengming Sun;Miao Liu;Yingang Zhang
Department of Orthopaedics, the First Affiliated Hospital of Xi' an Jiaotong University, Xi' an 710061, Shaanxi Province, ChinaDepartment of Orthopaedics, the First Affiliated Hospital of Xi' an Jiaotong University, Xi' an 710061, Shaanxi Province, ChinaDepartment of Orthopaedics, the First Affiliated Hospital of Xi' an Jiaotong University, Xi' an 710061, Shaanxi Province, China
基础医学
intervertebral disc degenerationanimal modelrabbit
intervertebral disc degenerationanimal modelrabbit
《南京医科大学学报（英文版）》 2008 (5)
骨髓间质干细胞椎间盘内异位分化及差异表达基因的研究
308-312,5
This study was supported by National Natural Science Foundation ofChina(30400163)
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