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两种乳化技术制备的爱普列特微球的特性研究

谭载友 廖清江 肖罗宾 苏丹尼

中国药科大学学报2003,Vol.34Issue(4):309-312,4.
中国药科大学学报2003,Vol.34Issue(4):309-312,4.

两种乳化技术制备的爱普列特微球的特性研究

Characteristics of Epristeride Microspheres with Two Emulsifying Preparation Methods

谭载友 1廖清江 2肖罗宾 3苏丹尼3

作者信息

  • 1. 广东药学院,广州,510224
  • 2. 中国药科大学,南京,210009
  • 3. 香港天高科技研究中心,香港
  • 折叠

摘要

Abstract

AIM:To develop epristeride control release microspheres and to assess the characteristics of epristeride microspheres, which were prepared by two ways. METHOD: Epristeride microsperes were prepared using a water-in-oil-in-water double emulsion technique and a oil-in-water emulsion technique by treatment of key of a minimal amount of PVA and NaCl, and were determined with bulk density, particle size, specific surface area, moisture content and dissolution. RESULT: Different preparations bring about difference in the characteristics of epristeride microspheres. CONCLUSION: High porous microsphere and low porous microsphere can be manufactured by treatment of key of PVA and NaCl in previous two ways respectively.

关键词

爱普列特/微球/制备/乳化技术/物理特征

Key words

Epristeride/Microsphere preparation/Emulsion technique/Physical characteristics

分类

医药卫生

引用本文复制引用

谭载友,廖清江,肖罗宾,苏丹尼..两种乳化技术制备的爱普列特微球的特性研究[J].中国药科大学学报,2003,34(4):309-312,4.

基金项目

国家"九五"科技攻关资助项目(编号96-902-01-01) (编号96-902-01-01)

中国药科大学学报

OA北大核心CSCDCSTPCD

1000-5048

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