癌症2001，Vol.20Issue(3)：311-313,3.
大肠癌ICAM-1的表达及临床意义
Expression of ICAM-1 in Colorectal Carcinoma and Its Clinical Significance
杨明智 1陈积圣 1伍衡 1王培戈 2张敬智 2李玉军3
作者信息
- 1. 中山医科大学孙逸仙纪念医院外科,
- 2. 青岛医学院附属医院外科,
- 3. 青岛医学院附属医院病理科,
- 折叠
摘要
Abstract
Objective：This study was designed to determine the expression of ICAM-1 in colorectal cancer and its clinical significance. Methods：The expression of ICAM-1 in 55 samples of colorectal carcinoma and 8 samples of adenomas were invested using immunohistochemical staining. Results：There were 41 positive cases in 55 colorectal cancer samples. The positive rate of ICAM-1 in colorectal cancer was significantly higher than that of adenomas （ P<0.05） , ICAM-1 in colorectal cancer was significantly correlated with lymph node metastasis. However， there was no significantly difference in ICAM-1 expression between adenomas and colorectal cancer without lymph node metastasis. Conclusion： Over-expression of ICAM-1 was significantly related to lymph node metastasis.关键词
细胞间粘附分子-1/大肠肿瘤/免疫组织化学分类
医药卫生引用本文复制引用
杨明智,陈积圣,伍衡,王培戈,张敬智,李玉军..大肠癌ICAM-1的表达及临床意义[J].癌症,2001,20(3):311-313,3.
