首页|期刊导航|南京医科大学学报(英文版)|A Streptococcus suis serotype 2 caused streptococcal toxic shock syndrome(STSS) in a patient
南京医科大学学报(英文版)2008,Vol.22Issue(5):313-316,4.
A Streptococcus suis serotype 2 caused streptococcal toxic shock syndrome(STSS) in a patient
A Streptococcus suis serotype 2 caused streptococcal toxic shock syndrome(STSS) in a patient
摘要
Abstract
Streptococcus suis (S. suis) is a Gram-positive, facultatively anaerobic coccus that has been implicated as the cause of a wide range of clinical disease syndromes in swine and other domestic animals. S. suis has also been implicated in disease in humans, especially among abattoir workers, swine and pork handlers. Here we report a case of streptococcal toxic shock syndrome(STSS) caused by S. suis in a 59-year-old man. Despite of intensive treatment, the patient died of shock with multiple organ failure 14 h after admission. One bacterial isolate obtained from blood culture was identified to the species level by biochemical tests and serological tests as S. suis serotype 2. Identification was confirmed by PCR amplification of genes encoding 16sRNA of S. suis and the capsule of S. suis serotype 2(cps 2J). Genes encoding virulence factors were also detected. An investigation to identify the source of S. suis revealed that several days before admission the affected man had been handling sick pigs or their meat. Transmission may occur through breaks in the skin of feet with tinea due to that no measures for personal protection was taken. This case should highten awareness of the potential for occupational exposure and human infection with S. suis.关键词
Streptococcus suis/streptococcal toxic shock syndrome/PCRKey words
Streptococcus suis/streptococcal toxic shock syndrome/PCR分类
医药卫生引用本文复制引用
Yefei Zhu,Chen Dong,Changjun Bao,Rongqiang Zhu,Fengcai Zhu,Hua Wang,Zhongmin Tan ,Lingyang Zhu,Hongxing Pan,Xuejun Zhang,Lei Xu,Huimin Qian,Ling Gu,Xun Ye..A Streptococcus suis serotype 2 caused streptococcal toxic shock syndrome(STSS) in a patient[J].南京医科大学学报(英文版),2008,22(5):313-316,4.基金项目
This study was supported by Jiangsu Provincial Natural Science Fund(BK2008463) (BK2008463)