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细胞相容性聚氨酯的合成及其细胞相容性研究

管建均 高长有 沈家骢

高等学校化学学报2001,Vol.22Issue(2):317-320,4.
高等学校化学学报2001,Vol.22Issue(2):317-320,4.

细胞相容性聚氨酯的合成及其细胞相容性研究

Preparation and Characterization of Cell Compatible Polyurethane

管建均 1高长有 1沈家骢1

作者信息

  • 1. 浙江大学高分子科学与工程系,
  • 折叠

摘要

Abstract

Cell compatible polyurethane(PU) was obtained by surface photo-grafting of 2-hydroxyethyl acrylate(HEA) onto PU membrane surface. Hydroperoxide groups were introduced onto PU membrane surface by photo-oxidization, then the oxidized membrane, immersed previously in monomer solution, was irradiated under UV light. The grafted copolymers were characterized by ATR-FTIR spectra, element spectroscopy for chemical analysis(ESCA) and static water contact angle. The results showed that grafting was confined within the surface layer. Cell compatible study revealed that the attachment and growth of human umbilical vein endothelial(HUVE) cells were improved after HEA grafting. Cells grew faster on the surface with higher oxygen content.

关键词

聚氨酯/接枝聚合/丙烯酸羟乙酯/内皮细胞/细胞相容性

分类

化学化工

引用本文复制引用

管建均,高长有,沈家骢..细胞相容性聚氨酯的合成及其细胞相容性研究[J].高等学校化学学报,2001,22(2):317-320,4.

基金项目

国家自然科学基金 ()

高等学校化学学报

OA北大核心CSCD

0251-0790

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