中德临床肿瘤学杂志（英文版）2007，Vol.6Issue(4)：319-321,3.
体部伽玛刀治疗原发性肝癌的疗效分析
The efficacy of stereotactic body radiotherapy for patients with hepatocellular carcinoma
Hongzhen Zhang 1Yazhen Wang 1Ning Xu 2Xinbo Duan 1Chaoying Ren1
作者信息
- 1. Department of Radiology,Hebei Province People's Hospital,Shijiazhuang 050051,China
- 2. The Hebei University of Science and Technology,Shijiazhuang 050051,China
- 折叠
摘要
Abstract
Objective: To evaluate efficacy of the stereotactic body radiotherapy for patients with hepatocellular carcinoma.Methods: Twenty-seven patients with hepatocellular carcinoma were treated by technique of stereotactic body radiotherapy.Planning of treatment was made and the prescribed dose was adjusted depending on the site of the tumor, clinical target volume (GTV), Kanofsky Performance and aim of treatment. Planning target volume received 50%-80% of the prescribed dose for 3.2-4.2 Gy per-fraction. Treatment total dose was 32-42 Gy (median dose 40 Gy) in daily fractions of 3.2-4.2 Gy for five fractions one week. Results: All the patients completed the planned radiotherapy. The tumor response rate was CR 25.9%, PR 55.6%, NR 18.59%; the response rate (CR + PR) was 81.5%. Half-year local recurrence-free survival rate was 75%; 1-year local recurrence-free survival rate was 22%. There were no serious complications during radiotherapy and follow-up. Pain relieve rate in liver region was 83.3%. Conclusion: Stereotactic body radiotherapy can improve the local control and quality of life on the treatment of primary hepatic neoplasm while not increasing the treatment complication.关键词
hepatoma/hepatocellular carcinoma/radiotherapy/stereotactic body radiotherapy/prognosisKey words
hepatoma/hepatocellular carcinoma/radiotherapy/stereotactic body radiotherapy/prognosis分类
医药卫生引用本文复制引用
Hongzhen Zhang,Yazhen Wang,Ning Xu,Xinbo Duan,Chaoying Ren..体部伽玛刀治疗原发性肝癌的疗效分析[J].中德临床肿瘤学杂志（英文版）,2007,6(4):319-321,3.
