河南医科大学学报2001，Vol.36Issue(3)：323-324,2.
涎腺肿瘤组织中P185蛋白的表达
The expression of P185 protein in salivary gland tumors
何巍 1刘学杰 1龚建民 1栗清朝 2石爱梅 1姜国城1
作者信息
- 1. 河南医科大学第一附属医院口腔颌面外科
- 2. 登封市第一人民医院口腔科
- 折叠
摘要
Abstract
Aim: To study the relationship between the expression of P185 protein in salivary gland tumor and the tumor biologic characteristics.Methods:Twenty cases of pleomorphic adenoma(PA),12 cases of adenolymphoma,19 cases of malignant pleomorphic adenoma(MPA) and 25 cases of adenoid cystadenoma carcinoma were examined to detect the neu gene product P185 protein by immunohistochemical SP method.Results:The positivity rate of P185 in MPA(57.9%) was significantly higher than that in PA(10.0%)(P＜0.05); The positivity rate of P185 in malignant salivary gland tumors with lymph node metastasis (100%)was significantly higher than that without(48.6%)(P＜0.05).Conclusion:P185 protein plays an important role in pleomorphic adenoma carcinogenesis;detection of P185 has the value of judging whether lymph node metastasis is present and providing scientific basis for selecting the operation pattern.关键词
P185蛋白/neu基因/涎腺肿瘤/免疫组织化学方法分类
医药卫生引用本文复制引用
何巍,刘学杰,龚建民,栗清朝,石爱梅,姜国城..涎腺肿瘤组织中P185蛋白的表达[J].河南医科大学学报,2001,36(3):323-324,2.
