耳鼻咽喉-头颈外科2001，Vol.8Issue(1)：32-34,3.
TNF-α及CD68在鼻息肉中的表达和意义
Expression of TNF\|α and CD68 in nasal polyps tissue and their significance
王成硕 1董震 1杨占泉1
作者信息
- 1. 长春白求恩医科大学附属第三临床学院耳鼻咽喉-头颈外科
- 折叠
摘要
Abstract
Objective: To study the expression of TNF\|α and CD68 in nasal polyps tissue and their significance. Methods. Paraffin sections of 19 nasal polyps and 8 chronic rhinitis samples were studied with immunohistochemical technique. Results. The expression of TNF\|α were stronger in nasal polyps tissues than that in controls. Numerous CD68 positive cells were found in epithelium laryer and in the lamina propria of nasal polyps. There were positive relationship between the expression of TNF\|α and that of CD68(r=0.615). Conclusion. It was suggested that activized macrophage as antigen\|presenting cell in the development of nasal polyps, may play a important role through upregulated TNF\|α′s synthesis and secretion.关键词
肿瘤坏死因子/鼻息肉/巨噬细胞分类
医药卫生引用本文复制引用
王成硕,董震,杨占泉..TNF-α及CD68在鼻息肉中的表达和意义[J].耳鼻咽喉-头颈外科,2001,8(1):32-34,3.
