河南医科大学学报2001，Vol.36Issue(3)：327-328,2.
国产醋氨己酸锌治疗消化性溃疡疗效观察
Curative effect of zinc acexamate on peptic ulcer
冯常炜 1崔广林 1李振峰 1赵治国 1唐芙爱 1段芳龄1
作者信息
摘要
Abstract
Aim: To evaluate the clinical efficacy and safety of zinc acexamate(ZAC) in treating peptic ulcer.Methods:A total of 135 patients with peptic ulcer proven by endoscopy entered arandomized double-blind,double-dummy study.Sixty eight patients received ZAC 0.3 g,3 times per day,including 47 with duodenal ulcer(DU) and 21 with gastric ulcer(GU);67 patients among whom 46 with DU and 21 with GU received cimitidine 0.2 g,3 times per day,and 0.4 g before sleeping in the evening.The course was DU 4 weeks,and GU 6 weeks.Results:There was no difference in DU and GU healing rates of ZAC group and cimitidine group(48% vs 52% and 69% vs 50%,P＞0.05).The pain relief rates of ZAC group and cimitidine group were similar(DU,70% vs 87% and GU,100% vs 86%,P＞0.05).The adverse reaction of ZAC group was 16%,and that of cimitidine group was 11%(P＞0.05).Conclusion:ZAC is an effective drug in the treatment of peptic ulcer.关键词
醋氨己酸锌/西米替丁/胃溃疡/十二指肠溃疡分类
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冯常炜,崔广林,李振峰,赵治国,唐芙爱,段芳龄..国产醋氨己酸锌治疗消化性溃疡疗效观察[J].河南医科大学学报,2001,36(3):327-328,2.
