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氯氮平诸效应的相关性与同源相关假说

喻东山 张心保 蒋晓军 孙旦晖 肖红 张石宁

中国临床康复2002,Vol.6Issue(21):3305-3306,2.
中国临床康复2002,Vol.6Issue(21):3305-3306,2.

氯氮平诸效应的相关性与同源相关假说

The correlations between effects in patients with schizophrenia receiving clozapine: same root correlation hypothesis

喻东山 1张心保 1蒋晓军 1孙旦晖 1肖红 1张石宁1

作者信息

  • 1. Brain Hospital Affiliated Nanjing Medical University ,Nanjing 210029,China
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摘要

Abstract

Objective To explore the correlations between effects in schizophrenics treated with clozapine.Method It was estimated for PANSS at baseline and 28th day as well as for serum clozapine level at 29th day in 66 schizophrenics receiving clozapine monotherapy.Results (1)There was all statistically significant positive correlations between 6 factors of TESS without coincident items;(2)Of 54 correlations between 6 factirs of TESS and 9 subtracting score rates of PANSS subscales.only 6 arrived statistically significant level;(3)Of 23 correlations between 9 subtracting score rates of PANSS subscales without coincident items, only 9 were statistically significant.Conclusion The same root correlation hypothesis in a narrow sense would be utility in future pharmacology.

关键词

schizophrenia/clozapine/same root correlation hypothesis

Key words

schizophrenia/clozapine/same root correlation hypothesis

分类

医药卫生

引用本文复制引用

喻东山,张心保,蒋晓军,孙旦晖,肖红,张石宁..氯氮平诸效应的相关性与同源相关假说[J].中国临床康复,2002,6(21):3305-3306,2.

中国临床康复

OACSTPCD

2095-4344

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