首页|期刊导航|南京医科大学学报（英文版）|Effects of bone morphogenetic protein on the osseointegration of porous-surfaced implants: An experimental study in rabbits
南京医科大学学报（英文版）2006，Vol.20Issue(6)：335-340,6.
Effects of bone morphogenetic protein on the osseointegration of porous-surfaced implants: An experimental study in rabbits
Effects of bone morphogenetic protein on the osseointegration of porous-surfaced implants: An experimental study in rabbits
摘要
Abstract
Objective: Research on enhancing early osseointegration of cementless implants to improve early fixation and reducing of risk of loosening. Methods: Thirty New Zealand rabbits were divided into two groups at random. BMP combined with DBM 30 mg was inserted around the prosthesis in 15 rabbits as experimental group, the remaining rabbits were served as control group. After 4, 8, and 12 weeks, five rabbits were sacrificed in each group. The humerus with the implants were retrieved.Bone ingrowth was analyzed by none-decalcification bone ground section and biomechanical test. Results: At the end of 4 and 8weeks the osseointegration rates of BMP group were higher than those of control (P ＜ 0.05). The ultimate shear strength between BMP treated implantation and the control was the same as the results in osseointegration rates at 4, 8 weeks (P ＜ 0.05). However,there was no difference between the treated and untreated group in the osseointegration rate and ultimate shear strength at 12 weeks (P ＞ 0.05). Conclusion: BMP combination can enhance bone growth into gaps around cementless implants, especially in the early postoperative period.关键词
osseointegration/BMP/implant fixation/rabbitKey words
osseointegration/BMP/implant fixation/rabbit分类
医药卫生引用本文复制引用
Yimin Ma,Weimin Fan,Yu Zhang..Effects of bone morphogenetic protein on the osseointegration of porous-surfaced implants: An experimental study in rabbits[J].南京医科大学学报（英文版）,2006,20(6):335-340,6.基金项目
Nanjing Medical University Fund(2001 ) （2001 ）
