中华医学杂志（英文版）2005，Vol.118Issue(1)：34-37,4.
Chronic idiopathic thrombocytopenic purpura in adult Chinese patients: a retrospective single-centered analysis of 1791 cases
Chronic idiopathic thrombocytopenic purpura in adult Chinese patients: a retrospective single-centered analysis of 1791 cases
LI Hong-qiang 1ZHANG Lei 1ZHAO Hui 1JI Lin-xiang 1YANG Ren-chi1
作者信息
- 1. Department of Thrombosis and Hemostasis, Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Tianjin 300020, China
- 折叠
摘要
Abstract
Background Adult chronic idiopathic thrombocytopenic purpura (ITP) is a common hematologic disease characterized by persistent thrombocytopenia. So far, there were only a few reports on adult Chinese patients with chronic ITP. This study aimed at defining the treatment outcome and prognostic factors for chronic ITP based on a large cohort of Chinese patients followed up for over 25 years at a single center.Methods The medical records of 1791 patients aged 14 years or older who were diagnosed as having chronic ITP at our hospital from 1974 to 1999 were retrospectively analyzed.Conclusions Adult Chinese chronic ITP patients can have long-term remission after steroid therapy and splenectomies. Primary steroid refractoriness is a prognostic factor predicting poor subsequent response to a splenectomy.关键词
idiopathic thrombocytopenic purpura/steroids/splenectomy/antiplatelet antibodyKey words
idiopathic thrombocytopenic purpura/steroids/splenectomy/antiplatelet antibody分类
医药卫生引用本文复制引用
LI Hong-qiang,ZHANG Lei,ZHAO Hui,JI Lin-xiang,YANG Ren-chi..Chronic idiopathic thrombocytopenic purpura in adult Chinese patients: a retrospective single-centered analysis of 1791 cases[J].中华医学杂志（英文版）,2005,118(1):34-37,4.
