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230例经腹腔镜胆囊切除术患者应用抗生素的成本-效果分析

左笑丛 刘世坤 谢冰玲

中国药房2001,Vol.12Issue(6):344-346,3.
中国药房2001,Vol.12Issue(6):344-346,3.

230例经腹腔镜胆囊切除术患者应用抗生素的成本-效果分析

Cost-effectiveness Analysis of the Antibiotic Application in 230 Patients Undergoing Laparoscopic Cholecystectomy

左笑丛 1刘世坤 1谢冰玲1

作者信息

  • 1. 中南大学湘雅三医院药剂科,
  • 折叠

摘要

Abstract

To explore the rational use of antibiotics in patients undergoing laparoscopic cholecystectomy(LC).METHODS: The antibiotic use in the selected operation patients was retrospectively studied.230 patients were divided into four groups.A group: Perioperative administration of drug; B group: Preoperative administration for 3 to 7 days and perioperative administration; C group: Perioperative administration and postoperative administration for 2 to 7 days; D group: Preoperative administration for 2 to 7 days, perioperative administration and postoperative administration for 2 to 7 days.Four groups were compared about the efficacy, length of hospital stay and hospitalization expenses.RESULTS: There were no significant differences in efficacy among A, B, C, D and in average length of hospital stay and hospitalization expenses between A and D groups.A group was the lowest in two indices and had the best cost-effectiveness ratio.CONCLUSION: There is clinical significance of preventive antibiotic application in LC patients; perioperative use is the best choice; Cefazolin is the first choice.

关键词

腹腔镜胆囊切除术/抗生素应用/成本-效果分析

分类

医药卫生

引用本文复制引用

左笑丛,刘世坤,谢冰玲..230例经腹腔镜胆囊切除术患者应用抗生素的成本-效果分析[J].中国药房,2001,12(6):344-346,3.

中国药房

1001-0408

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