中德临床肿瘤学杂志（英文版）2009，Vol.8Issue(6)：353-355,3.DOI:10.1007/s10330-009-0033-7
血清乳酸脱氢酶、β2微球蛋白测定对非霍奇金淋巴瘤病情及预后判断的价值
Prognostic values of serum LDH and β2-MG in patients with non-Hodgkin's lymphoma
Lei Yang 1Xiaohong Xu 1Chunlei Peng 1Jinzhi Wei 1Zhuchen Song 1Zhirong Cong1
作者信息
- 1. Department of Medical Ontology, Nantong Tumor Hospital, Nantong 226361, China
- 折叠
摘要
Abstract
Objective: To evaluate the clinical significance of quantitative determinafion of serum lactic dehydrogenase (LDH) and beta 2-microglobulin (β2-MG) in patients with non-Hodgkin's lymphoma (NHL). Methods: Date of the 65 patients from 2003 to 2004 were retrospectively analyzed, relationship between LDH and β2-MG activities and tumor phase, effect of treat-ment as well as prognosis were studied. Results: The levels of LDH and β2-MG in the advanced stage, B group and bone marrow involvement were obviously higher than their comparison counterpart and the difference was significant (P < 0.05). There was no significant difference between the high LDH group and normal LDH group in the two-year survival rate. But the difference in the four-year survival rate was significance. Conclusion: The level of LDH and β2-MG are valuable for clinical stage, prognosis and evaluation of therapeutic response in patients with NHL.关键词
lactic dehydrogenase/beta 2-microglobulin/non-Hodgkin's lymphoma/prognosisKey words
lactic dehydrogenase/beta 2-microglobulin/non-Hodgkin's lymphoma/prognosis分类
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Lei Yang,Xiaohong Xu,Chunlei Peng,Jinzhi Wei,Zhuchen Song,Zhirong Cong..血清乳酸脱氢酶、β2微球蛋白测定对非霍奇金淋巴瘤病情及预后判断的价值[J].中德临床肿瘤学杂志（英文版）,2009,8(6):353-355,3.
