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影响骨髓间充质干细胞增殖的调节因素及其信号转导途径

袁琳 宋关斌

生物技术通报Issue(7):35-38,41,5.
生物技术通报Issue(7):35-38,41,5.

影响骨髓间充质干细胞增殖的调节因素及其信号转导途径

Study of Key Factors for the Proliferation of Bone Marrow Mesenchymal Stem Cells and Their Signal Transduction

袁琳 1宋关斌1

作者信息

  • 1. 重庆大学生物工程学院,重庆,400044
  • 折叠

摘要

Abstract

Bone marrow-derived mesenchymal stem cells (MSCs) are a kind of somatic stem cells. Many physical and chemical factors, such as extracellular matrix, cytokine and mechanical stimulation, play an important role in the proliferation of the cells through various signal transduction pathways. Meanwhile, it often presents cross-talking and interaction among those pathways. This paper focused on the review of the progress of the extracellular matrix, cytokine and mechanical stimulation on the proliferation of MSCs and their signal transduction.

关键词

诱导多能干细胞/重编程/肿瘤形成/诱导效率/替代因子

Key words

Bone marrow-derived mesenchymal stem cells Proliferation Extracellular matrix Cytokine Mechanical stimulation Signal transduction

分类

医药卫生

引用本文复制引用

袁琳,宋关斌..影响骨髓间充质干细胞增殖的调节因素及其信号转导途径[J].生物技术通报,2009,(7):35-38,41,5.

基金项目

国家自然科学基金资助项目(30770530),教育部留学回国人员基金资助项目(教外司留[2007]1108-9) (30770530)

生物技术通报

OA北大核心CSCD

1002-5464

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