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有机和有机金属多酸化合物生物活性研究

刘景福 王晓红 孙振刚 李恒达

应用化学2001,Vol.18Issue(5):357-359,3.
应用化学2001,Vol.18Issue(5):357-359,3.

有机和有机金属多酸化合物生物活性研究

Bioactivity of Organic and Organometallic Substituted Polyoxometalates

刘景福 1王晓红 1孙振刚 1李恒达1

作者信息

  • 1. 东北师范大学化学学院
  • 折叠

摘要

Abstract

A number of organotin, cyclopentadienyltitanium, cyclopentadienylzirconium andorganophosphoryl substituted polyoxometalates are reported in relation of their antitumor activity a-gainst SSMC-7721 and Hela human tumor ceils. The cyclopentadienyltitanium polyoxometalatesshowed higher activity than other compounds with the same polyanions. CoW11CpTi was found tohave higher antitumor activity and low toxicity as showed in vivo tests. It is also observed that the or-der of the antitumor activity of complexes is in relation with the order of the redox behavior of thepolyanions.

关键词

有机金属/多酸化合物/抗肿瘤活性

分类

化学化工

引用本文复制引用

刘景福,王晓红,孙振刚,李恒达..有机和有机金属多酸化合物生物活性研究[J].应用化学,2001,18(5):357-359,3.

应用化学

OA北大核心CSCD

1000-0518

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