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理气活血中药调整应激大鼠免疫和血液流变性的机理研究

钱瑞琴 杨宇 蒋文跃

中国中西医结合杂志2001,Vol.21Issue(5):364-366,3.
中国中西医结合杂志2001,Vol.21Issue(5):364-366,3.

理气活血中药调整应激大鼠免疫和血液流变性的机理研究

Study on Modulation Effect of Qi Regulating and Blood Activating Drugs on Mechanism of Immunity and Hemorrheology in Stressed Rats

钱瑞琴 1杨宇 1蒋文跃1

作者信息

  • 1. 北京大学医学部基础医学院中西医结合教研室北京 100083
  • 折叠

摘要

Abstract

Objective: To explore the modulation effect of Chinese herbalmedicines for Qi regulating and blood activating (QRBA) on mechanism of immunity and hemorrheology in stressed rats. Methods: The influence of QRBA on plasma noradrenaline (NA), proliferation of splenic cells and hemorrheologic properties were observed in stressed rats. Results: The Chinese herbal medicines for soothing Liver to regulate Qi, activating blood circulation to remove stasis and QRBA drugs could antagonize in various degrees the changes caused by stress. Amony them QRBA drugs was the best, it could reduce the level of plasma NA (P<0.01), modulate the blood hyper-viscosity induced by exogenous NA (P<0.05) and enhance proliferation of splenic cells (P<0.01) in rats. Conclusion: QRBA drugs strengthen immune function and restore hemorrheologic properties by reducing NA content in organism.

关键词

应激/免疫/血液流变性/理气活血中药

分类

医药卫生

引用本文复制引用

钱瑞琴,杨宇,蒋文跃..理气活血中药调整应激大鼠免疫和血液流变性的机理研究[J].中国中西医结合杂志,2001,21(5):364-366,3.

基金项目

卫生部科研基金资助项目(94-1-277) (94-1-277)

中国中西医结合杂志

OA北大核心CSCDMEDLINE

1003-5370

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