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单核苷酸多态性与法医学DNA分型技术

Allah Rakha 杨丽 李生斌

法医学杂志2007,Vol.23Issue(5):373-379,7.
法医学杂志2007,Vol.23Issue(5):373-379,7.

单核苷酸多态性与法医学DNA分型技术

SNPs and Forensic DNA typing

Allah Rakha 1杨丽 1李生斌1

作者信息

  • 1. 西安交通大学卫生部法医学重点实验室,环境与疾病相关基因教育部重点实验室,陕西,西安,710061
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摘要

Abstract

There is an increasing interest in single nucleotide polymorphism (SNP) typing in the forensic field.SNPs are very useful for deftning Y chromosome or mtDNA haplotypes and DNA phenotyping.We focus on comparative advantages of SNP typing over length variations and expected number of loci required to gain probabilities equal to sTR loci in use.This review also offers to the reader a state of the art of SNP genotyping technologies with the advantages and disadvantages of the different techniques and platforms for different forensic requirements.

关键词

单核苷酸多态性/SNP分型/常染色体SNPs/DNA表型

Key words

single nucleotide polymorphism (SNP)/SNP genotyping/Autosomal SNPs/DNA phenotyping

分类

社会科学

引用本文复制引用

Allah Rakha,杨丽,李生斌..单核苷酸多态性与法医学DNA分型技术[J].法医学杂志,2007,23(5):373-379,7.

法医学杂志

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