安徽中医学院学报2001，Vol.20Issue(2)：37-40,4.
大鼠脾虚证与血清甲状腺激素及下丘脑、胸腺细胞核T3受体关系
RELATIONSHIP BETWEEN SPLEEN-ASTHENIA SYNDROME AND SERUM THYROXIN,T3 RECEPTORS OF HYPOTHALAMUS CELLS & THYMUS T LYMPHOCYTE NUCLEI IN RATS
摘要
Abstract
Objective：To study the relationship between Spleen-asthenia syndrome and serum thyroxin,T3 receptors of hypothalamus cells & thymus T lymphocyte nuclei in rats.Method:Rhubarb decoction was used to develop spleen-asthenia syndrome in SD adult rat.32 rats were averagely divided into four groups at random：Group A(control group),group B(spleen-asthenia group),group C(group treated with Sijunzi decoction),group D(spontaneous rehabilitation group).The radioimmunoassay was applied to measure serum thyroxin levels and the contents of T3 receptors of hypothalamus cells and thymus T lymphocyte nuclei of every rat.Result:The serum levels of T3，T4，FT3，FT4，the contents of T3 receptors of hypothalamus cells and thymus T lymphocyte nuclei in group B,D were lower than those in group A,C.The difference between them was significant.Serum level of γ-T3 in four groups had no significant difference.Conclusion:The decline of T3,T4,FT3,FT4 serum levels,and the contents of nuclear T3 receptors in hypothalamus cells & thymus T lymphocytes can influence the activity of thyroxin,then the immunity function will be impaired via neuroendocrinimmunology net(NEI net),this may be a kind of important pathogensis of spleen-asthenia syndrome.关键词
脾虚证/甲状腺激素/下丘脑细胞/胸腺细胞/细胞核T3受体分类
医药卫生引用本文复制引用
李刚,夏天,王宗仁,张仲海..大鼠脾虚证与血清甲状腺激素及下丘脑、胸腺细胞核T3受体关系[J].安徽中医学院学报,2001,20(2):37-40,4.基金项目
国家自然科学基金资助课题 （）
