中国临床康复2002，Vol.6Issue(24)：3766-3767,2.
医用生物蛋白胶对注射型骨形态发生蛋白成骨活性的影响
Influence of fibrin sealant on osteoinductive ability of inject-type bone morphogenetic protein
王登虎 1刘建 1李丹 1胡蕴玉 1袁志1
作者信息
- 1. Xijing Hospital,Fourth Military Medical University,Xi'an 710032,China
- 折叠
摘要
Abstract
Objective To observe influence of fibrin sealant(FS) on osteoinductive ability of inject type BMP.Method The inject type BMP power was dissolved in the main glue part or thrombin part of FS, then mixed with the main glue part or thrombin part of FS into gel, observe coagulating time, then implant composite into the thigh muscle pouch of mice to evaluate their capacity to induce new bone formation, and compared to the single BMP implant group.Result There was no difference in the coagulating time between two mixing method, the osteoinductive ability of implants BMP dissolved in the main glue part or thrombin part of FS group was higher than that of simply BMP implant group.Conclusion FS was perfect carrier to inject type BMP. 关键词
bone morphogenetic protein/fibrin sealant/basic fibroblast growth factor/carrierKey words
bone morphogenetic protein/fibrin sealant/basic fibroblast growth factor/carrier分类
医药卫生引用本文复制引用
王登虎,刘建,李丹,胡蕴玉,袁志..医用生物蛋白胶对注射型骨形态发生蛋白成骨活性的影响[J].中国临床康复,2002,6(24):3766-3767,2.
