Comparative Research on Serogroups Distribution and Antimicrobial Resistance of Escherichia coil Isolates from Poultry in Different Areas of ChinaOA
Comparative Research on Serogroups Distribution and Antimicrobial Resistance of Escherichia coil Isolates from Poultry in Different Areas of China
A total of 241 Escherichia coli(E. coli)isolates from 349 avian samples(292 from cloacae,29 from feed and water,28 from dust and padding)were collected from Northeast,South,North,and Central China in recent years.The percentage of isolation was 69.1%.There are 67 serogroups each with 1-2 isolates distributed in different regions.and some of these regions had the preponderant serogroups.Antimicrobial-resistance(AR)of E. coli was so severe that the majority were multi-AR.Fifty percent strains were resistant to 10-19 antimicrobial drugs.Overall,the isolates represented resistance to nalidixic acid(88.1%),tetracycline(85.7%),sulfamethoxazole(81.0%),trimethoprim-sulfamethpxazole(77.1%),ampicillin (76.2%),amoxilline(74.3%),streplomycin(66.2%),fluoroquinolones(57.1-66.7%),chloramphenicol(52.9%),gentamicin (39.0%),and kanamycin(36.2%).The isolates were sensitive to cefalexin,amoxilline-clavulanic acid,amikacin,and florfenicol with all AR rate of 0-19.5%only.The results showed that the AR was more severe in chicken farms in which the antibiotics were used broadly and repeatedly.This study indicated the AR characterization of E. coli in different areas of China.It will be a foundation for studying AR mechanism and regulating the usage of antimicrobial in the poultry industry.
A total of 241 Escherichia coli(E. coli)isolates from 349 avian samples(292 from cloacae,29 from feed and water,28 from dust and padding)were collected from Northeast,South,North,and Central China in recent years.The percentage of isolation was 69.1%.There are 67 serogroups each with 1-2 isolates distributed in different regions.and some of these regions had the preponderant serogroups.Antimicrobial-resistance(AR)of E. coli was so severe that the majority were multi-AR.Fifty percent strains were resistant to 10-19 antimicrobial drugs.Overall,the isolates represented resistance to nalidixic acid(88.1%),tetracycline(85.7%),sulfamethoxazole(81.0%),trimethoprim-sulfamethpxazole(77.1%),ampicillin (76.2%),amoxilline(74.3%),streplomycin(66.2%),fluoroquinolones(57.1-66.7%),chloramphenicol(52.9%),gentamicin (39.0%),and kanamycin(36.2%).The isolates were sensitive to cefalexin,amoxilline-clavulanic acid,amikacin,and florfenicol with all AR rate of 0-19.5%only.The results showed that the AR was more severe in chicken farms in which the antibiotics were used broadly and repeatedly.This study indicated the AR characterization of E. coli in different areas of China.It will be a foundation for studying AR mechanism and regulating the usage of antimicrobial in the poultry industry.
SONG Li;FENG Zhong-wu;NING Yi-bao;ZHANG Xiu-ying;SHENG Qing-chun;ZHANG Guang-chuan;LIN Shu-mao;WU Hao-ting;ZHAO Hui;GAO Guang
China Institute of Veterinary Drug Control,Beijing 100081,P.R.ChinaChina Institute of Veterinary Drug Control,Beijing 100081,P.R.ChinaChina Institute of Veterinary Drug Control,Beijing 100081,P.R.ChinaChina Institute of Veterinary Drug Control,Beijing 100081,P.R.ChinaChina Institute of Veterinary Drug Control,Beijing 100081,P.R.ChinaFoshan College ofScience and Technology,Foshan 528000.P.R.ChinaChina Institute of Veterinary Drug Control,Beijing 100081,P.R.ChinaChina Institute of Veterinary Drug Control,Beijing 100081,P.R.ChinaChina Institute of Veterinary Drug Control,Beijing 100081,P.R.ChinaChina Institute of Veterinary Drug Control,Beijing 100081,P.R.China
畜牧业
Escherichia coli,serogroups,antimicrobial-resistance
Escherichia coli,serogroups,antimicrobial-resistance
《中国农业科学（英文版）》 2008 (3)
381-386,6
The work was supported by the National Key Technologies R&D Program of China During the 10th Five-Year Plan period (2002BA514A-17-10).We thank Dr.Dai Lei for review of the English version of this article.
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