中国科学院研究生院学报2002，Vol.19Issue(4)：382-387,6.
肌肉收缩中横桥间的协作行为
Cooperative Behaviors of Cross-Bridges in Muscle Contraction
摘要
Abstract
According to swinging cross-bridge model, muscle contraction is produced by cyclical attachment and detachment of cross-bridges towards thin filament. The cooperative behaviors of cross-bridges in muscle isotonic contraction in one dimensional condition is investigated. Firstly, we suppose a relationship between energy and time for a single cross-bridge during the working cycle. Then we investigate two particular cooperative behaviors of crossbridges in muscle isotonic contraction(in which the extern load F is constant):(1)n0 attached cross-bridges work at the same tempo, the working process is not affected by the environment; (2)n0 attached cross-bridges work at the same tempo, and the working rate is proportional to the very velocity of thin filament in the contraction. We have calculated the relationship between the extern load to muscle and the velocity of muscle contraction in the two conditions. We find that in the first case it is similar to the Hill curve in shape, and in the second case the velocity is inversely proportional to the force.关键词
肌肉收缩/分子马达/协作行为Key words
muscle contraction/molecular motors/cooperative behaviors分类
数理科学引用本文复制引用
胡锋,蔡勖..肌肉收缩中横桥间的协作行为[J].中国科学院研究生院学报,2002,19(4):382-387,6.基金项目
supported by the National Natural Science Foundation of China under Grand No. 10075022 （）
