老年心脏病学杂志（英文版）2009，Vol.6Issue(1)：38-41,4.
Blood pressure circadian rhythm and heart rate turbulence in hypertensive patients: relationship with left ventricular hypertrophy
Blood pressure circadian rhythm and heart rate turbulence in hypertensive patients: relationship with left ventricular hypertrophy
Mei Zhu 1Mohan Liu 1Xinhong Guo 1Shiwen Wang1
作者信息
- 1. Institute of Geriatric Cardiology, Chinese PLA General Hospital, Beijing 100853, China
- 折叠
摘要
Abstract
Objective To investigate the relationship of blood pressure circadian rhythm with myocardial hypertrophy and the changes of autonomic nerve function in patients with essential hypertension (EH). Methods Eighty-two female patients with essential hypertension (EH) underwent 24-hours ambulatory blood pressure monitorings (ABPM), dynamic electrocardiogram (Holter) and echocardiography examination. Patients were classified into non-dipping group (n=40) and dipping group (n=42) according to the result of ABPM. Left ventricular mass index (LVMI), heart rate variability (HRV) in time domain (including SDNN, SDANN, rMSSD, PNN50) and heart rate turbulence (HRT) parameters (including turbulence onset [TO] and turbulence slope [TS]) were measured. Results Compared with those in dipping group, patients in non-dipping group have higher incidence of LVH (19.0% vs 52.5%, P<0.01), greater mean LVMI (112.39±12.79 g/m2 vs 121.98±13.35 g/m2, P<0.01), decreased PNN50 and rMSSD. TS value was decreased while TO was increased in non-dipping group compared with those in dipping group (both P <0.01); patients with LVH showed decreased TS and increased TO, compared with those without LVH. Conclusion In female patients with EH, non-dipping blood pressure circadian is associated with higher incidence of LVH. The HRV and HRT were more remarkably blunted in non-dipping patients, as well as those with LVH.关键词
Hypertension/myocardial hypertrophy/heart rate variability/heart rate turbulenceKey words
Hypertension/myocardial hypertrophy/heart rate variability/heart rate turbulence分类
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Mei Zhu,Mohan Liu,Xinhong Guo,Shiwen Wang..Blood pressure circadian rhythm and heart rate turbulence in hypertensive patients: relationship with left ventricular hypertrophy[J].老年心脏病学杂志（英文版）,2009,6(1):38-41,4.
