中国现代医学杂志2007，Vol.17Issue(4)：389-393,5.
医用羟基磷灰石纳米粒的制备和特性:羟基磷灰石纳米粒的纳米结构及纳米尺寸效应
Synthesis and characterization of hydroxyapatite nanoparticles for medicine utilization: nanostructure and nanosize effect of hydroxyapatite nanomaterials
李国政 1张阳德 1张洪 1李钧 1魏坤2
作者信息
- 1. 卫生部纳米生物技术重点实验室,湖南,长沙,410008
- 2. 华南理工大学材料科学与工程学院,广州,510640
- 折叠
摘要
Abstract
[Objective] To prepare a kind of hydroxyapatite nanoparticle for medical utilization and to observe its nanostructure and nanosize effect. [Method] The nanoparticles of hydroxyapatite (HA) had been synthesized using normal (oil in water) surfactant. Ultrastructure of nanoparticles was studied through HRTEM, FTIR, NMR, XRD.[Results] The experimental results showed that the size of nanorod samples was about 10～30 nm. The presence of these resonance of phosphorus in at least two types of phosphorus environments. The spectra of nanorod contained typical bands of hexahedra Ca2+ at 200 nm. The Eg values for the HA of microcrystalline, nanorod samples were 1.60and 1.64ev, respectively. The FTIR spectra of the nanorods include two types of vibration; three PO43- stretching modes at 956.5, 1 026.1 and 1 108.7cm-1 band were attributed to the v1 (PO4), v3 (PO4), v3 (PO4) modes respectively. Two PO43- bending modes at 565.2 and 600.0 cm-1 bands were attributed to the v4(PO4) modes. [Conclusion] A minor increase of edge energy of nanorods to microcrystalline resulted in by nanosize might be associated with a decrease in cluster sized as well as the ligand changes around Ca2+ ions. These changes might relate to quantum size effect.关键词
羟基磷灰石/纳米粒/纳米结构/纳米尺寸效应Key words
hydroxyapatite/nanorods/nanostructure/nanosize effect分类
医药卫生引用本文复制引用
李国政,张阳德,张洪,李钧,魏坤..医用羟基磷灰石纳米粒的制备和特性:羟基磷灰石纳米粒的纳米结构及纳米尺寸效应[J].中国现代医学杂志,2007,17(4):389-393,5.
