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腰神经根损伤后神经细胞粘附分子(N-CAM)在神经肌肉接头部的表达

周重建 侯宝兴 王拥军 刘梅 施杞

中国临床康复2003,Vol.7Issue(29):3962-3964,3.
中国临床康复2003,Vol.7Issue(29):3962-3964,3.

腰神经根损伤后神经细胞粘附分子(N-CAM)在神经肌肉接头部的表达

Expression of neural cell adhesion molecule at neuromuscular junction after lumber nerve root injury

周重建 1侯宝兴 2王拥军 1刘梅 1施杞1

作者信息

  • 1. 上海中医药大学脊柱病研究所,上海市,200032
  • 2. 上海中医药大学附属龙华医院伤骨科,上海市,200032
  • 折叠

摘要

Abstract

AIM: To investigate the expression of neural cell adhesion molecule(N-CAM) at the neuromuscular junction after lumber nerve root injury.METHODS: The distribution changes of N-CAM at flatfish muscle neuro-muscular junction of rat in its embryon phase, 14-day after birth, adulthood and 10, 20 and 30 days after its L5 lumber nerve root injury were observed by immunohistochemistry and confocal laser scanning microscopy technologies.RESULTS: N-CAM at muscle canal surface and neuromuscular junction were dyed intensively in strength at the embryon phase in rat, and the strength decreased during its growth and almost disappeared in its adulthood. However,N-CAM's repetition appeared after the innervation loss in muscle.Expression of N-CAM is regulated by the condition of nerve control.

关键词

脊神经根/神经肌肉接头/神经再生/N-CAM

分类

医药卫生

引用本文复制引用

周重建,侯宝兴,王拥军,刘梅,施杞..腰神经根损伤后神经细胞粘附分子(N-CAM)在神经肌肉接头部的表达[J].中国临床康复,2003,7(29):3962-3964,3.

基金项目

上海市科委自然科学基金资助项目(02 ZB 14089) (02 ZB 14089)

中国临床康复

OACSTPCD

2095-4344

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