中国临床康复2003,Vol.7Issue(29):3962-3964,3.
腰神经根损伤后神经细胞粘附分子(N-CAM)在神经肌肉接头部的表达
Expression of neural cell adhesion molecule at neuromuscular junction after lumber nerve root injury
摘要
Abstract
AIM: To investigate the expression of neural cell adhesion molecule(N-CAM) at the neuromuscular junction after lumber nerve root injury.METHODS: The distribution changes of N-CAM at flatfish muscle neuro-muscular junction of rat in its embryon phase, 14-day after birth, adulthood and 10, 20 and 30 days after its L5 lumber nerve root injury were observed by immunohistochemistry and confocal laser scanning microscopy technologies.RESULTS: N-CAM at muscle canal surface and neuromuscular junction were dyed intensively in strength at the embryon phase in rat, and the strength decreased during its growth and almost disappeared in its adulthood. However,N-CAM's repetition appeared after the innervation loss in muscle.Expression of N-CAM is regulated by the condition of nerve control.关键词
脊神经根/神经肌肉接头/神经再生/N-CAM分类
医药卫生引用本文复制引用
周重建,侯宝兴,王拥军,刘梅,施杞..腰神经根损伤后神经细胞粘附分子(N-CAM)在神经肌肉接头部的表达[J].中国临床康复,2003,7(29):3962-3964,3.基金项目
上海市科委自然科学基金资助项目(02 ZB 14089) (02 ZB 14089)