摘要
Abstract
Objective:To investigate the clinical features,pathological characteristics and immunophenotype of solid-pseudopapillary tumor of the pancreas(SPTP).Methods:Nine surgically treated cases of SPTP were retrospectively reviewed.Hematoxylin and Eosin(HE)staining and immunohistochemical staining were used to analyze all cases,and the general clinical data was collected.Results:Six patients were asymptomatic except for a palpable mass.Two patients complained of vague-epigastric pain.One patient appeared jaundice.The tumor was encapsulated and solid tissues alternately with cystic tissues.Histologically,the histological structure of solid portion was pseudopapillary with a fibrovascular core.Tumor cells were uniform and medium-sized which were arranged in sheets ets or nests or pseudopapillary patterns.Immunohistochemical studies demonstrated that SPTP proved positive in vimenfin(9/9 cases),AAT(9/9 cases),,NSE(9/9 cases),ACT(7/9 cases),CK20(2/9 cases),CgA(1/9 cases),S-100(3/9cases),PR(4/9cases),Syn(3/9 cases)and CD56(5/9cases),negative in CEA and ER.Conclusion:SPTP is a tumor predominantly occurring in young women frequently without special symptoms.This tumor has various characteristical histological patterns with different immunophenotype.关键词
pancreatic neoplasm/solid-pseudopapillary tumor/pancreasKey words
pancreatic neoplasm/solid-pseudopapillary tumor/pancreas分类
医药卫生
