赣南医学院学报2009，Vol.29Issue(3)：399-401,3.
依达拉奉对急性脑梗死患者血清IL-17、IL-6和TNF-α的影响
Effects of Edaravone on the Levels of Serum IL-17,IL.6,and TNF-α in Patients with Acute Cerebral Infarction
陈骏 1熊春霖 1郭文超2
作者信息
- 1. 中山市横栏医院
- 2. 中山市人民医院,广东,中山,528403
- 折叠
摘要
Abstract
Objective:To study effects of edaravone on the levels of serum intedeukin-17 (IL-17),IL-6,tumor necrosis factor-α (TNF-α) in patients with acute cerebral infarction.Methods:63 patients of cerebral infarction were randomly divided and assigned to edaravone group and control group.31 patients in control group were treated by routine therapy of acute cerebral infarction two weeks.Another 32 patients in edaravone group were treated with routine therapy and edaravone for two weeks.The levels of serum IL-17,IL-6,and TNF-α were measured by enzyme-linked immunusorbent assay before treatment and after treatment 7d and 14d.Results:Although there were no difference before treatment and after treatment 7d,the levels of serum IL-17,IL-6,and TNF-α were found to be sharply decreased in edaravone group compared with the control group after treatment 14d.The levels of serum IL-17,IL-6,and TNF-α in two groups were lower significantly after treatment 7d and 14d than before treatment.Conclusions:Edaravone can decrease the levels of serum IL-17,IL-6,and TNF-α,which probably reduce the injury of ischemic brain and improve therapeutic efficacy.关键词
依达拉奉/脑梗死/IL-17/IL-6/TNF-αKey words
Edaravone/Cerebral infarction/IL-17/IL-6/TNF-α分类
医药卫生引用本文复制引用
陈骏,熊春霖,郭文超..依达拉奉对急性脑梗死患者血清IL-17、IL-6和TNF-α的影响[J].赣南医学院学报,2009,29(3):399-401,3.
