首页|期刊导航|中国海洋湖沼学报(英文版)|Expression of nitric oxide synthase in the developing eye of Zebrafish Danio rerio
中国海洋湖沼学报(英文版)2004,Vol.22Issue(4):399-402,4.
Expression of nitric oxide synthase in the developing eye of Zebrafish Danio rerio
Expression of nitric oxide synthase in the developing eye of Zebrafish Danio rerio
摘要
Abstract
Expression of nitric oxide synthase (NOS) in the developing eye of zebrafish was studied by NADPH-diaphorase staining technique. NOS activity was first observed in the optic primordium and the lens placode at 5-somite stage, and remained basically unchanged up to the prim-5 stage. Upon hatching, NOS activity was nearly equally detected in the gangalion cell layer and the photoreceptor layer in the developing retina. However, it began declining in the inner plexiform layer and the inner nuclear layer at this stage. NOS activity disappeared in the lens although the anterior lens epithelium was strongly stained. Two days after hatching, NOS activity was still strong in the photoreceptor layer, but decreased markedly in the gangalion cell layer, the inner plexiform layer and the inner nuclear layer with the retinal patterning. These suggested that nitric oxide (NO), the product of NOS, is not only involved in the modulation of patterning and differentiation of the retinal cells but also in the regulation of proliferation, and differentiation of the lens fibrocytes.关键词
nitric oxide/eye development/zebrafishKey words
nitric oxide/eye development/zebrafish分类
海洋科学引用本文复制引用
WANG Yongjun,ZHANG Shicui,M S. Sawant..Expression of nitric oxide synthase in the developing eye of Zebrafish Danio rerio[J].中国海洋湖沼学报(英文版),2004,22(4):399-402,4.基金项目
The work was supported by Ministry of Science and Technology (MOST) of China (G1999012006). (MOST)